Gelatine for hard and soft capsules
Soft capsules, manufactured with a blend of gelatines, glycerol and/or sorbitol and water, are utilised to contain substances of various kind; the filling and the production of the capsules is made at the same time.
There are soft capsules of various shapes and colours and can contain several types of active principles, usually liquid substances.
Soft capsules are normally manufactured using a medium bloom gelatine.
Hard capsules are manufactured following the technique of immersion; two half capsules are produced and are then assembeld minly by the pharmaceutical companies which fill in the capsules with active principles and provide for the directly sealing.
Hard capsules are manufactured using high bloom gelatine
Gelatine for tablets
For this application the adhesive properties of gelatine are exploited to give structure to the tablet.
Gelatine is submitted to wet granulation before the compression. The bloom value of the gelatine employed is essential for the dissolution of the tablet.
High bloom value for longer times, low bloom value for more rapid times of dissolution.
Hydrolysed gelatine is used for direct compression.
Gelatine for micro-encapsulation
Micro-encapsulation allows to change the solubility and the aspect of a substance (oil from liquid to powder), or to cover unpleasant odour or taste of the substance.
Micro-encapsulation can also protect the substance from oxidation or humidity.
The substance which has to be micro-encapsulated is finely dispersed in a gelatine solution and then transformed in a powder thanks to a further particular process of drying.